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At Rise Therapeutics, we develop targeted immunological-based biologics using a unique and proprietary oral delivery platform. We design and produce unique, first-in-class immune modulatory drugs for the treatment of inflammation, autoimmunity, infection, and cancer.

Rise Therapeutics Begins Operations of its GMP Manufacturing Facility

Rockville, MD. Rise Therapeutics announced today that they have successfully initiated operations of their GMP manufacturing facility based in Rockville, MD.  Funding to help set up this GMP manufacturing operation came from the National Institute of Health (NIH) Commercialization Readiness Pilot (CRP) Program Grant, which assists small businesses with technical assistance and late-stage development projects that are not typically supported by SBIR and STTR Phase II and Phase IIB grants. Launching of operations for this facility was also supported by the financial contributions of the Montgomery County Economic Development Corporation.  

Rise Therapeutics Secures Funding to Develop a Novel, Immunologically Enhanced Probiotic Medicine for Treating Cancer

Rockville, MD. Rise Therapeutics, a company that develops innovative immune therapies, announced today that it initiated a new program to develop a novel, immunologically enhanced microbiome drug for the treatment of cancer. This product candidate, R-5780, engages key immune pathways regulated by the microbiome to enhance the effectiveness of immune checkpoint inhibitor (ICI) therapy to treat cancer. Coinciding with the timing of this release, Rise has secured funding to support key product development initiatives for the program.

Rise Therapeutics Announces Publication of an Important Peer-Reviewed Journal Article Related to its R-3750 Program

Rockville, MD. Rise Therapeutics, a biotechnology company developing first-in-class targeted immunological-based biologics using a unique and proprietary oral delivery platform, announced today the publication of the co-authored article, “Lactococcus lactis Delivery of Surface Layer Protein A Protects Mice from Colitis by Re-Setting Host Immune Repertoire” in the journal Biomedicines.

Rise Therapeutics Announces Publication of a New Article Related to its R-5780 Program

Rockville, MD. Rise Therapeutics, a biotechnology company developing first-in-class targeted immunological-based biologics using a unique and proprietary oral delivery platform, highlighted today a new publication in the journal Science that highlights mechanisms by which the microbiota engage host immune pathways to improve immunotherapy. The article examines recent pre-clinical studies that found that the peptidoglycan hydrolase Secrete Antigen A (SagA) is able to promote immunotherapy responses and synergize with immune checkpoint inhibitors (ICI) to drive tumor regression in animal model studies. These results support development of novel synthetic biology medicines to be used in conjunction with ICI therapy.

Rise Therapeutics Granted a Small Business Innovation Research Matching Grant from the Montgomery County

Rockville, MD. Rise Therapeutics today announced that Montgomery County has issued Rise Therapeutics a $25,000 Small Business Innovative Research (SBIR) grant matching award. This funding was awarded based upon Montgomery County’s SBIR/STTR Matching Grant Program and will be used to further Rise Therapeutics’ research project efforts to develop novel microbiome-based medicines,

Rise Therapeutics Hires Sathya Janardhanan, MS as Vice President of Development and Manufacturing

Rockville, MD. Rise Therapeutics, a synthetic biology company developing targeted immunological-based biologics using a unique and proprietary oral delivery platform, today announced the appointment of Sathya Janardhanan, MS, as Vice President of Development and Manufacturing.