Rise Therapeutics Secures Funding to Develop a Novel, Immunologically Enhanced Probiotic Medicine for Treating Cancer
Rockville, MD. Rise Therapeutics, a company that develops innovative immune therapies, announced today that it initiated a new program to develop a novel, immunologically enhanced microbiome drug for the treatment of cancer. This product candidate, R-5780, engages key immune pathways regulated by the microbiome to enhance the effectiveness of immune checkpoint inhibitor (ICI) therapy to treat cancer. Coinciding with the timing of this release, Rise has secured funding to support key product development initiatives for the program.
Rise Therapeutics Announces Publication of an Important Peer-Reviewed Journal Article Related to its R-3750 Program
Rockville, MD. Rise Therapeutics, a biotechnology company developing first-in-class targeted immunological-based biologics using a unique and proprietary oral delivery platform, announced today the publication of the co-authored article, “Lactococcus lactis Delivery of Surface Layer Protein A Protects Mice from Colitis by Re-Setting Host Immune Repertoire” in the journal Biomedicines.
Rise Therapeutics is taking on immunotherapy from a slightly different pathway – the gut microbiome.
In the context of normal human biology, the microbiome is a collection of microorganisms, including bacteria, fungi, viruses, and other microbes, that reside in various bodily habitats, including our gut. Gary Fanger, Founder, President and Chief Executive Officer of Rockville-based Rise Therapeutics, explains that the microbiome needs to be seen in light of a new organ in the body.
The Montgomery County Economic Development Corporation (MCEDC) awarded a total of $96,430 to six small life science companies as part of its recently completed Bio Lab Pilot Project. The project was launched in 2019 to assist local growth-stage life science companies with their wet lab and infrastructure needs. Applicants seeking financial help to build out small wet lab space less than 5,000 SF were encouraged to apply for $10 per SF of lab fit out costs, up to $30,000 per company. Project funding was provided by MCEDC and the Maryland Department of Commerce.
Rise Therapeutics Receives Wet Lab Buildout Grant from Montgomery County Economic Development Corporation
Rockville, MD. Rise Therapeutics today announced that the Montgomery County Economic Development Corporation (MCEDC) Fund’s Bio Lab Pilot Project issued Rise Therapeutics funding to support its clinical GMP manufacturing infrastructure build out. This grant supports a key corporative initiative for Rise Therapeutics to expand its product development infrastructure in the microbiome space to include capabilities that enable the organization to more efficiently and cost effectively transition cutting-edge microbiome discoveries into clinically validated drug products. This MCEDC funding program supports $10 per square foot of lab fit out costs to build out wet lab space up to 5,000 square feet.
Rockville, MD. Rise Therapeutics, a biotechnology company developing first-in-class targeted immunological-based biologics using a unique and proprietary oral delivery platform, highlighted today a new publication in the journal Science that highlights mechanisms by which the microbiota engage host immune pathways to improve immunotherapy. The article examines recent pre-clinical studies that found that the peptidoglycan hydrolase Secrete Antigen A (SagA) is able to promote immunotherapy responses and synergize with immune checkpoint inhibitors (ICI) to drive tumor regression in animal model studies. These results support development of novel synthetic biology medicines to be used in conjunction with ICI therapy.